SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL STUDIES OF SOME TRANSITION METAL COMPLEXES WITH 1-PHENYLBUTANE-1,3-DIONE AND ETHYLENEDIAMINE

Abstract

In this study, tetraaza macrocyclic ligand was prepared by condensation of 1-phenylbutane-1,3-dione and thylenediamine in ethanol. Its metal (II) complexes were synthesized from the chloride salts of Cd(II), Co(II), Cu(II), Ni(II) and Zn(II). The compounds were characterized on the basis of solubility, melting/decomposition temperatures, FT-IR, molar conductance and magnetic moments. The antibacterial activity of all synthesized compounds has been evaluated against Staphylococcus aureus and Escherichia coli using agar cup-plate method. The FT-IR spectra of the ligand showed band at 1655cm-1 due to azomethine which confirms the formation of the ligand. This peak shifted towards the lower frequencies of 1628cm-1, 1596cm-1, 1611cm-1, 1600cm-1 and 1600cm-1 in the spectra of Cd(II), Co(II), Cu(II), Ni(II), Zn(II) complexes respectively which is attributed to the binding of the nitrogen of azomethine to the metal ions. The ligand and its complexes were found to be active against both Staphylococcus aureus and Escherichia coli.